DermaGene® Cellular Longevity 2-Step Skin Renewal System
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DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System

DermaGene® Cellular Longevity 2-Step Skin Renewal System

Two steps. One smarter way to support stressed, ageing skin. 800 ppm NAD⁺ and 3,000 ppm PDRN pair daily renewal with barrier recovery to help skin look smoother, plumper, calmer and more resilient. A simple serum + cream ritual for skin that feels tired, dry, overtreated or slower to bounce...
2.774,00 Kč
3.015,00 Kč
2.774,00 Kč
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Ingredients
Ingredients
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Package includes:

  • 1 x DermaGene® NAD⁺ Radiant Longevity Serum (30 ml)
  • 1 x DermaGene® PDRN2000 Cellular Recovery Cream (50 ml)

DermaGene® NAD⁺ Radiant Longevity Serum 0.08% NAD⁺ + 1000 ppm PDRN Anti-Aging Firming Serum

Ingredients: Water, Glycerin, Propylene Glycol, Polyglycerin-10, 1,2-Hexanediol, Hydroxyacetophenone, Resveratrol, Carbomer, Triethanolamine, Panthenol, Hydrolyzed Collagen, Sodium Hyaluronate, Mannitol, Sodium DNA, Phenoxyethanol, Nicotinamide Adenine Dinucleotide, Disodium EDTA, Sodium Chloride, Ethylhexylglycerin, Leuconostoc/Radish Root Ferment Filtrate, Copper Tripeptide-1, Sh-Polypeptide-1

DermaGene® PDRN2000 Cellular Recovery Cream (50 ml)

Ingredients (INCI):Water, Cetearyl Alcohol, Glycerin, Ethylhexyl Palmitate, Polyglycerin-10, Caprylic/Capric Triglyceride, Dimethicone, PEG-20 Stearate, Lauric/Myristic/Palmitic/Stearic Glycerides, Hydroxyacetophenone, 1,2-Hexanediol, Centella Asiatica Leaf Extract, Hydrolyzed Collagen, Glyceryl Stearate, Carbomer, Sodium DNA, Carnosine, Sodium Hyaluronate, Potassium Hydroxide, Panthenol, Disodium EDTA, Sodium Lauroyl Lactylate, Citric Acid, Ceramide NP, Ceramide AP, Phytosphingosine, Cholesterol, Xanthan Gum, Mannitol, Phenoxyethanol, Sodium Chloride, Ethylhexylglycerin, Ceramide EOP, sh-Polypeptide-1.

Description
Description
x

Two steps. One smarter way to support stressed, ageing skin. 800 ppm NAD⁺ and 3,000 ppm PDRN pair daily renewal with barrier recovery to help skin look smoother, plumper, calmer and more resilient. A simple serum + cream ritual for skin that feels tired, dry, overtreated or slower to bounce back. For daily renewal and recovery.

Shipping & Return
Shipping & Return
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Fast, flexible & fully tracked delivery from within the EU.

• Zone 1 — Central Europe: Austria, Germany, Romania, Slovakia — from €5.90 (2–4 business days)

• Zone 2 — Extended Europe: Bulgaria, Croatia, Czechia, Poland, Slovenia — from €6.90 (3–7 business days)

• Zone 3 — Europe Wide: Belgium, Denmark, Estonia, France, Greece, Italy, Latvia, Lithuania, the Netherlands, Portugal, Spain — from €9.90 (3–7 business days)

• Zone 4 — Northern & Atlantic Europe: Finland and Sweden from €9.90; Ireland from €27.90 (4–8 business days)

Free standard EU delivery on all orders over €160.
Choose from Packeta Pickup Point or Locker, Packeta Home Delivery and GLS Home Delivery.
Cash on Delivery is available in selected countries for orders up to €300, with a fixed €7.90 service fee.

Orders placed before 12:00 CET on business days are normally dispatched the same day.
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Returns: Easy 14-day returns with personal support from our Customer Care team.

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DermaGene® Cellular Longevity 2-Step Skin Renewal System

DermaGene® Cellular Longevity 2-Step Skin Renewal System

3.015,00 Kč 2.774,00 Kč
DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System
DermaGene® Cellular Longevity 2-Step Skin Renewal System

DermaGene® Cellular Longevity 2-Step Skin Renewal System

3.015,00 Kč 2.774,00 Kč

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When your skin stops bouncing back like it used to.

Dullness, dryness, fine lines and increased sensitivity can all be signs that your skin needs more than another layer of moisture. Cellular Longevity pairs concentrated renewal with serious barrier care in two simple daily steps. The serum works first with NAD⁺, PDRN and advanced antioxidants; the cream follows with 2,000 ppm PDRN and barrier-supporting lipids to leave skin looking calmer, fuller and visibly healthier.

Renew first. Recover second.

This routine is built around a simple idea: skin looks its best when renewal and recovery stay in balance. STEP 1 targets tired, dull and less resilient-looking skin with longevity-focused actives. STEP 2 replenishes moisture and supports the barrier with PDRN, ceramides and soothing ingredients. Together, they create an easy AM + PM ritual for skin that looks smoother, stronger and well-rested.

NAD⁺ 800 ppm

The longevity-focused hero of STEP 1. NAD⁺ brings a new approach to tired, stressed-looking skin, supporting a fresher, more energised and revitalised appearance.

Resveratrol + GHK-Cu

The serum pairs 0.5% Resveratrol with Copper Tripeptide-1 (GHK-Cu) for antioxidant and peptide-focused care. Together, they support a smoother, firmer-looking complexion while complementing the routine's longevity approach.

PDRN 3,000 ppm Across the Routine

1,000 ppm PDRN in the serum + 2,000 ppm in the recovery cream. A two-step approach created around skin recovery, hydration and a plumper, smoother, more resilient-looking complexion.

Ceramide Barrier Complex

Ceramide NP, AP and EOP, together with cholesterol, phytosphingosine and panthenol, make STEP 2 much more than a moisturiser. This lipid-rich system supports the skin barrier, helping skin feel less dry, more comfortable and better protected.

Use with your device- Enhance results

Designed for Electrocosmetic Treatments & Advanced Skin Devices

Radiofrequency . Microcurrent. EMS. LED. Ultrasound. These treatments can do a lot for the skin — but afterwards, it often just feels like it needs a bit of calm.

That’s where Cellular Longevity comes in. The two-step routine is designed to be compatible with many electro-cosmetic protocols, sitting comfortably alongside them and giving skin a simple renewal + recovery step after more intensive treatments. With ingredients like PDRN, ceramides, panthenol and hydrating agents, it helps support comfort and the skin barrier when skin feels a bit dry, tight or reactive.

Your device does the work. Your skincare helps your skin settle afterwards.

Always follow the instructions and post-treatment skincare guidance provided with your specific beauty device or professional treatment.

DERMAGENE®

Not inspired by clinics.
Developed within them.

Every technology we include was validated by aesthetic professionals and physicians — delivering complete home aesthetic protocols, not standalone devices.

AWARD-WINNING  ·  17 YEARS  ·  40,000+ DEVICES ACROSS EUROPE  ·  CE CERTIFIED

RECOGNIZED BY ELLE  ·  MARIE CLAIRE  ·  JOY  ·  GLAMOUR  ·  FORBES

Scientific Background

The Cellular Longevity 2-Step System brings together two complementary approaches to skin ageing: cellular-focused care and barrier recovery. NAD⁺ is a naturally occurring coenzyme involved in cellular energy metabolism and DNA repair, while the serum combines it with 1,000 ppm PDRN, 0.5% resveratrol and GHK-Cu for a multi-active longevity approach. STEP 2 follows with 2,000 ppm PDRN, ceramides, cholesterol, phytosphingosine, panthenol and Centella asiatica to focus on recovery, hydration and barrier support. Human research on PDRN has demonstrated significantly greater re-epithelialisation after 7 days (p < 0.008), while studies of ceramide-rich lipid combinations show significantly accelerated barrier recovery with consistent topical use. Together, the two formulas are designed around a simple principle: support skin renewal, then give the barrier what it needs to recover.

Scientific Background & References

Rubegni, P., et al. “Clinical Evaluation of the Trophic Effect of Polydeoxyribonucleotide (PDRN) in Patients Undergoing Skin Explants: A Pilot Study.” Current Medical Research and Opinion, vol. 17, no. 2, 2001, pp. 128–131. doi:10.1185/030079901317010793.

De Paepe, Kristien, et al. “Repair of Acetone- and Sodium Lauryl Sulphate-Damaged Human Skin Barrier Function Using Topically Applied Emulsions Containing Barrier Lipids.” Journal of the European Academy of Dermatology and Venereology, vol. 16, no. 6, 2002, pp. 587–594. doi:10.1046/j.1468-3083.2002.00527.x.

Gao, Meiyan, et al. “Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study.” 2025.

FAQs

A NAD⁺ and PDRN skincare routine combines longevity-focused ingredients with targeted recovery and barrier care. The DermaGene® Cellular Longevity System contains 800 ppm NAD⁺ and a total of 3,000 ppm PDRN across its two formulas, alongside peptides, antioxidants, ceramides and hydrating ingredients.

The routine can complement many at-home beauty device protocols. Use the products according to the instructions of your specific device, with PDRN2000 particularly suited to the recovery phase when skin needs hydration, comfort and barrier support. Always follow your device manufacturer's guidance on compatible skincare.

PDRN2000 was formulated with 2,000 ppm PDRN, ceramides, panthenol, Centella asiatica and hyaluronic acid to support hydration, comfort and the skin barrier. This makes the system particularly relevant when skin feels dry, stressed or sensitised from an intensive skincare routine.

Apply the NAD⁺ Radiant Longevity Serum first to clean skin, then follow with PDRN2000 Cellular Recovery Cream. The two formulas are designed to work as a simple renewal-and-recovery routine rather than requiring multiple layers of skincare.

Instead of focusing only on hydration or wrinkles, the system brings together NAD⁺, PDRN, GHK-Cu, resveratrol and a multi-ceramide barrier complex. The result is a more complete approach focused on visible skin renewal, firmness, hydration and barrier support — in just two steps.

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